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All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”

Laboratory of Experimental Therapy

of Experimental Therapy

Head of Laboratory,Arkhipov I. A. - Laboratory of pharmacology, toxicology and therapy   
Doctor of Veterinary Medicine, Professor,
Laureate of Government prize of the Russian Federation
Ivan Alekseevich Arkhipov

The laboratory, founded the Institute, is conducting a search for the most effective chemotherapy drugs and formulations for combating parasitic diseases of mammals, birds and fish; studying the pharmacokinetics and pharmaco-Toxicological properties of antiparasitic drugs and their impact on reproductive ability, milk production, body weight gain, immune status determines the residual amount of drugs in the body and the waiting periods after animal treatment.

The laboratory developed new technologies for antiparasitic biopolymer microencapsulated, liposomal, combined dosage forms and therapeutic crmov with anthelmintic.

Developed and tested the following medicines: tilidin, microencapsulated nattamon, Naftalan, bifen, saline, tetranet, azinoks, bunamidine (Bund), platinol, acetica, Penhaligon, fenapes, pegIFN, Lymfoven, evercel, boluses, prolonged action with Silverman, etc.

Recently offered for introduction: antaram against trematodes, anal – monitise, fetal – strongylatosis ruminants, biphenyl and binol – against paramphistomosis cattle, and fetal albendazole against nematodes in pigs, Termokarstovoye blend talk – insecticide for disinfection and desacarisation of livestock buildings. Developed a promising dosage form: Presiden helminthiasis of horses, Vivisol with nematodes in wild boar, the new combination of medicinal forms on the basis of praziquantel with albendazole or C1 aversectin when cestodosis of animals.

Installed toxicity, embryotrophic action, mutagenic and carcinogenic activity of the developed drugs, to determine their residues in organs and tissues of animals, as well as maximum permissible levels of therapeutic drugs in foods.

Refined tools and methods of removing embryotrophic action of anthelmintic some of benzimidazolecarbamate.

The methods of determining residual amounts of active substances (albendazole, medamine, fenbendazole, etc.) and their metabolites are released with the feces of treated animals, in soil, water, plants, and their impact on the functioning and development of capobianco and aquatic organisms.